Klara Schloß was born in Laudenbach/ District Bad Mergentheim on June 27, 1868 as the daughter of Mayer David and Sara Schloß, née Ullmann. In 1891, she married the merchant Ludwig Dreifuß in Zell near Würzburg. The couple had two daughters who were born in Lichtenfels/ Oberfranken (Upper Franconia) in 1892 and 1895. In 1898, Klara’s husband died. Between 1908 and 1918, Klara lived with her mother in Würzburg and worked there as an employee of the Louis Hamburger Company.

In May 1918, Klara Dreifuß moved to Bad Kissingen and initially lived in Maxstrasse 5 with Bamberger. Her daughter Ella had already worked in Bad Kissingen in the fashion shop of Felix Ehrlich in June 1916 and lived in a rented place with the Hamburger siblings in Hartmannstrasse 1. Later she lived at mother’s place in Maxstrasse before she moved to Heilbronn in October 1921. Klara’s oldest daughter Selma, who was an accountant just like her sister, had moved from Wiesbaden to her mother in Bad Kissingen in October 1919. Apart from a short stay in Berlin (1923-24), she lived in the Franconian spa till October 1933, before she went to Den Haag. In her file, however, there is also mentioned that she moved to Stuttgart in November 1937. 

In the 1930s, Klara Schloß also lived in Bad Kissingen in Theresienstrasse before she moved to Wiesbaden into Ellenbogengasse where her sister Julie, married Baum lived in November 1937. Julie Baum and Klara Dreifuß were deported to Theresienstadt via Frankfort on September 1, 1942 on transport XII/2, train number Da 509. On the death notice Nr. 12652 of the Elders’ Council of Theresienstadt Ghetto it is documented that Klara Dreifuß, custody number 638, living in building Nr. Q 317, room c7 died on November 20, 1942 at 8:30 A.M. at the age of 74. Death inspector, medical officer, and chief doctor certified “inflammation of the lungs and bronchial catarrh” as reason of death. Presumably, the horrible living conditions in the ghetto were responsible for her death. Klara Dreifuß was buried on November 22, 1942 at 3 P.M. (Notice of death Nr. 12652, holocaust.cz, quoted according to: Erinnerungsblätter in Bad Neustadt Wiesbaden Spiegelgasse). 

Klara’s daughter Ella (Ellen D. Samson) succeeded in emigrating to the USA, she lived in New York. Her older daughter was also successful in fleeing there. In March 1938, 45-year-old Selma Dreifuß left Wiesbaden, went on board the ship “Hansa” in Hamburg and emigrated to New York.